Search results for "general [Radio continuum]"

showing 10 items of 56936 documents

SARS-CoV-2 envelope protein topology in eukaryotic membranes

2020

Coronavirus E protein is a small membrane protein found in the virus envelope. Different coronavirus E proteins share striking biochemical and functional similarities, but sequence conservation is limited. In this report, we studied the E protein topology from the new SARS-CoV-2 virus both in microsomal membranes and in mammalian cells. Experimental data reveal that E protein is a single-spanning membrane protein with the N-terminus being translocated across the membrane, while the C-terminus is exposed to the cytoplasmic side (Nt lum /Ct cyt ). The defined membrane protein topology of SARS-CoV-2 E protein may provide a useful framework to understand its interaction with other viral and ho…

virusescoronavirusmedicine.disease_causeViral Envelope Proteinsmembrane insertionPeptide sequencelcsh:QH301-705.5Topology (chemistry)PhylogenyCoronavirusMutationChemistryGeneral NeuroscienceProteïnes de membranaEukaryotavirus diseases129Recombinant ProteinsCell biologysars-cov-2MembraneProtein topologyCoronavirus InfectionsResearch Article1001topologyPneumonia ViralImmunologySequence alignmentBiologyTopologiaVirusGeneral Biochemistry Genetics and Molecular BiologyBetacoronavirusCoronavirus Envelope ProteinsViral envelopeMicrosomesmedicineHumansAmino Acid SequencePandemicsResearchCell MembraneCOVID-1915envelope proteinMembrane proteinlcsh:Biology (General)CytoplasmMutationSequence AlignmentOpen Biology
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Enhancement by TNF-alpha of reactivation and replication of latent herpes simplex virus from trigeminal ganglia of mice.

1995

The influence of tumor-necrosis-factor-alpha (TNF-alpha), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukine-1 (IL-1) and IL-3 on the in vitro reactivation frequency and replication rate of trigeminal ganglia of mice latently infected with herpes simplex virus (HSV) strain KOS was studied. It could be demonstrated that TNF-alpha and possibility GM-CSF, but not IL-1 and IL-3, enhanced the reactivation frequency and replication of HSV. Interferon alpha/beta (IFN alpha/beta) prevented reactivation and replication.

virusesmedicine.medical_treatmentHerpesvirus 1 HumanBiologymedicine.disease_causeVirus ReplicationVirusHerpesviridaeMiceInterferonVirologyAlphaherpesvirinaeChlorocebus aethiopsmedicineAnimalsHumansVero CellsMice Inbred BALB CTumor Necrosis Factor-alphaGranulocyte-Macrophage Colony-Stimulating FactorInterferon-alphaGeneral MedicineInterferon-betabiology.organism_classificationVirologyIn vitroVirus LatencyCytokineHerpes simplex virusViral replicationTrigeminal GanglionInterleukin-3Virus Activationmedicine.drugInterleukin-1Archives of virology
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A Perturbed Cauchy Viscoelastic Problem in an Exterior Domain

2023

A Cauchy viscoelastic problem perturbed by an inverse-square potential, and posed in an exterior domain of RN, is considered under a Dirichlet boundary condition. Using nonlinear capacity estimates specifically adapted to the non-local nature of the problem, the potential function and the boundary condition, we establish sufficient conditions for the nonexistence of weak solutions.

viscoelastic problem; hardy potential; exterior domain; nonexistencenonexistenceSettore MAT/05 - Analisi MatematicaGeneral MathematicsComputer Science (miscellaneous)hardy potentialexterior domainEngineering (miscellaneous)viscoelastic problem
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Hölder regularity for the gradient of the inhomogeneous parabolic normalized p-Laplacian

2018

In this paper, we study an evolution equation involving the normalized [Formula: see text]-Laplacian and a bounded continuous source term. The normalized [Formula: see text]-Laplacian is in non-divergence form and arises for example from stochastic tug-of-war games with noise. We prove local [Formula: see text] regularity for the spatial gradient of the viscosity solutions. The proof is based on an improvement of flatness and proceeds by iteration.

viscosity solutionsApplied MathematicsGeneral Mathematicsta111010102 general mathematicsMathematical analysisparabolic01 natural sciencesNoise (electronics)non-homogeneouslocal C-alpha regularityTerm (time)010101 applied mathematicsViscosityBounded functionNon homogeneousEvolution equationp-Laplacian0101 mathematicsnormalized p-LaplacianFlatness (mathematics)MathematicsCommunications in Contemporary Mathematics
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Regularity for nonlinear stochastic games

2015

We establish regularity for functions satisfying a dynamic programming equation, which may arise for example from stochastic games or discretization schemes. Our results can also be utilized in obtaining regularity and existence results for the corresponding partial differential equations. peerReviewed

viscosity solutionsDiscretization01 natural sciencesMathematics - Analysis of PDEsBellman equationComputingMethodologies_SYMBOLICANDALGEBRAICMANIPULATIONFOS: MathematicsApplied mathematicstug-of-war0101 mathematicsMathematics - Optimization and ControlMathematical PhysicsMathematicsstokastiset prosessitPartial differential equationApplied Mathematics91A15 35J92 35B65 35J60 49N60010102 general mathematicsta111dynamic programming principletug-of-war with noise with space dependent probabilities010101 applied mathematicsNonlinear systemOptimization and Control (math.OC)p-LaplaceAnalysisAnalysis of PDEs (math.AP)
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Remarks on regularity for p-Laplacian type equations in non-divergence form

2018

We study a singular or degenerate equation in non-divergence form modeled by the $p$-Laplacian, $$-|Du|^\gamma\left(\Delta u+(p-2)\Delta_\infty^N u\right)=f\ \ \ \ \text{in}\ \ \ \Omega.$$ We investigate local $C^{1,\alpha}$ regularity of viscosity solutions in the full range $\gamma>-1$ and $p>1$, and provide local $W^{2,2}$ estimates in the restricted cases where $p$ is close to 2 and $\gamma$ is close to 0.

viscosity solutionsintegrability of second derivativesType (model theory)01 natural sciencesDivergencelocal C1ViscosityMathematics - Analysis of PDEsFOS: Mathematicspartial differential equations0101 mathematicsMathematicsMathematical physicsosittaisdifferentiaaliyhtälötα regularityApplied Mathematics010102 general mathematicsta111p-Laplacianlocal C1α regularityviskositeettiDegenerate equation35J60 35B65 35J92010101 applied mathematicsviscosityp-LaplacianAnalysisAnalysis of PDEs (math.AP)Journal of Differential Equations
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Fractional Hardy inequalities and visibility of the boundary

2013

We prove fractional order Hardy inequalities on open sets under a combined fatness and visibility condition on the boundary. We demonstrate by counterexamples that fatness conditions alone are not sufficient for such Hardy inequalities to hold. In addition, we give a short exposition of various fatness conditions related to our main result, and apply fractional Hardy inequalities in connection to the boundedness of extension operators for fractional Sobolev spaces.

visibility of the boundaryPure mathematicsMathematics::Functional AnalysisInequalityfractional Hardy inequalitiesGeneral Mathematicsmedia_common.quotation_subject010102 general mathematicsVisibility (geometry)46E35 (26D15)Open setMathematics::Classical Analysis and ODEsOrder (ring theory)Boundary (topology)01 natural sciences010101 applied mathematicsMathematics - Classical Analysis and ODEsClassical Analysis and ODEs (math.CA)FOS: Mathematics0101 mathematicsMathematicsExposition (narrative)media_common
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(A,B) In vivo GCaMP6f signals recorded in layers M1, M5 and M9/10 of Mi1 (A) and Tm3 (B) neurons, before (blue, green) and after (gray, red) applicat…

2019

Sensory systems sequentially extract increasingly complex features. ON and OFF pathways, for example, encode increases or decreases of a stimulus from a common input. This ON/OFF pathway split is thought to occur at individual synaptic connections through a sign-inverting synapse in one of the pathways. Here, we show that ON selectivity is a multisynaptic process in the Drosophila visual system. A pharmacogenetics approach demonstrates that both glutamatergic inhibition through GluClα and GABAergic inhibition through Rdl mediate ON responses. Although neurons postsynaptic to the glutamatergic ON pathway input L1 lose all responses in GluClα mutants, they are resistant to a cell-type-specifi…

visionQH301-705.5GABA AgentsScienceModels Neurological610Sensory systemBiologyStimulus (physiology)distributed codingGeneral Biochemistry Genetics and Molecular BiologySynapseglutamatergic inhibition03 medical and health sciencesGlutamatergic0302 clinical medicinePostsynaptic potentialOff pathwayInterneuronsAnimalsVisual PathwaysExcitatory Amino Acid AgentsBiology (General)030304 developmental biology0303 health sciencesGeneral Immunology and MicrobiologyGABAergic inhibitionD. melanogasterON selectivityGeneral Neurosciencefeature extractionQRGeneral MedicineD. melanogaster; GABAergic inhibition; ON selectivity; distributed coding; feature extraction; glutamatergic inhibition; neuroscience; visionVisual PerceptionMedicineGabaergic inhibitionDrosophilaSelectivityNeuroscience030217 neurology & neurosurgeryResearch ArticleNeuroscience
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Motion perception in early glaucoma

2013

Purpose: The aim of our study was to underline the changes in the movement perception for early glaucoma. Our working hypothesis consisted in inquiring if the impairment of the magnocellular pathway may modify the movement perception capabilities in the visual field, more particularly in its peripheral area.Methods: We included 14 healthy subjects and 14 patients with early primary open angle glaucoma. A moving target was presented on a semicircular screen (1.8 m diameter); participants were asked to localize the Ending Point (EP) of each movement. Each stimulus consisted in a white dot (0,72° of diameter) moving horizontally with the imposed velocity profile. Two different laws of motion w…

visual fieldmedicine.medical_specialty641 perceptiongenetic structuresOpen angle glaucoma758 visual fieldsGlaucomaperceptionStimulus (physiology)Standard deviationchamp visuel03 medical and health sciences0302 clinical medicineOptics[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyOphthalmologymedicineMotion perception[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs030304 developmental biologyganglion0303 health sciences[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology531 ganglion cellsbusiness.industryGeneral MedicineEarly glaucomacellmedicine.diseasePeripheralVisual fieldOphthalmology[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory Organs030221 ophthalmology & optometrycellulebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyActa Ophthalmologica
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Visual Methodologies and Geography's education in the pandemic time: notes on geopolitics of migration in the "Mediterranean Complex"

2022

<abstract> <p>The relationship between Geography and the Visual has always been strong intertwined. As it is true that Geography has always operates through images (in the form of pictures, creative representations and above all cartographies), in the last two years, with the distance learning due to the spread of the Covid-19 pandemic, this phenomenon has not only increased, but it also became necessary. "The classroom as the most radical space", in the words of bell hooks, had to turn into a virtual space, where images have a fundamental role in the teaching/learning process. This paper wants to analyse the relationship between Geography and the Visual by analysing three image…

visual geography education Covid-19 counter-visualities Mediterranean complexGeneral MedicineSettore M-GGR/01 - GeografiaAIMS Geosciences
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